Moe Sato is a young lady who finds a cat and starts taking care of him. Named Poyo due to his round shape, he quickly becomes a dear member of the Sato family. 
 
(Source: Anime News Network)

Episode 1 - All About the Round Cat...

Episode 2 - Forever With the Sphere

Episode 3 - The Sphere and Kuro

Episode 4 - The Sphere's Three Neighbors

Episode 5 - Come In, Sphere

Episode 6 - When With a Sphere, Do as the Sphere Does!

Episode 7 - Snow Falling on Spheres

Episode 8 - Come, Sphere

Episode 9 - The Sphere Has Been Waiting for You

Episode 10 - The Sphere Stood Up

Episode 11 - The Sphere is Nice and Warm

Episode 12 - The Season of the Sphere

Episode 13 - The Sphere of Blessings

Episode 14 - The Hated Sphere

Episode 15 - Sphere Snapshots

Episode 16 - The Sphere Fights

Episode 17 - The Sphere Weather

Episode 18 - A Real Ladies' Sphere

Episode 19 - Sphere Baldness

Episode 20 - Mysterious Sphere

Episode 21 - The Sphere's Habits

Episode 22 - Sphere Magistrate

Episode 23 - Drizzle, Drizzle, Sphere, Sphere

Episode 24 - Rain and Toads on Spheres

Episode 25 - Let's Do Some Sphere-ious Tidying

Episode 26 - Spherely-Poly

Episode 27 - The Bamboo Leaves Rustle in the Spheres

Episode 28 - The Summer-Colored Sphere

Episode 29 - Summer All A-Round

Episode 30 - Aloha Sphere

Episode 31 - The Roundest Day of the Summer

Episode 32 - Round Summer Mystery

Episode 33 - The Lantern Festival Should Be Round

Episode 34 - Rumble, Flash, Spheres Pouring Down

Episode 35 - Next to the Sphere Was Another Sphere

Episode 36 - The Sphere Circled Round or Whatever 

Episode 37 - Fur Everywhere, Spheres Everywhere

Episode 38 - Because the World is So Round

Episode 39 - It Was a Sphere Like a Lantern

Episode 40 - As Autumn Deepens, What Does the Sphere Do?

Episode 41 - A Fighting Sphere Shot!

Episode 42 - I Found a Tiny Sphere 

Episode 43 - Read, See, Sphere

Episode 44 - Round, Round, Grumble and Frown

Episode 45 - It Was a Sphere Tastier Than a Chestnut

Episode 46 - The Sphere of Warring States, Round 1

Episode 47 - The Sphere of Warring States, Round 2

Episode 48 - With Love and Spheres

Episode 49 - Sneeze Three Times, Take Three Spheres

Episode 50 - Where There Are Spheres in Life, Life is All Spheres.

Episode 51 - Round the End of the Year

Episode 52 - Until We Come 'Round Again

Studio DEEN

DAX Production

Dream Creation

Möbius Tone

Poyopoyo(2012)

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Poyopoyo.css-1qyv5d2{margin-left:0.6rem;font-size:0.9rem;color:#6c6c6c;}@media (min-width: 481px){.css-1qyv5d2{font-size:1.2rem;}}(2012)

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Recommendations

Poyopoyo(2012)